產(chǎn)品名稱 Cabozantinib S-malate - XL 184
產(chǎn)品貨號(hào) Axon 1819 CAS [1140909-48-3] MF C28H24FN3O5.C4H6O5MW 635.59 Purity: 99% Soluble in DMSO Description A orally available and potent inhibitor of multiple receptor tyrosine kinases (RTK), specifically MET and VEGFR2. It also inhibits KIT, FLT3, Tie-2, RET and AXL References Certificates Categories Extra info M Yakes et al.?Cabozantinib (XL184), a novel MET and VEGFR2 inhibitor, simultaneously suppresses metastasis, angiogenesis, and tumor growth. Mol. Cancer Ther. 2011, 10(12), 2298-2308.? Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology Axl c-MET FLT3 VEGFR c-KIT RTK class IV and X; EC 2.7.10.1 Inhibitor of multiple receptor tyrosine kinases, specifically MET and VEGFR2 Chemical name N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate Parent CAS No. [849217-68-1] Order Size Unit Price Stock 10 mg €85.00 In Stock
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Cabozantinib S-malate - XL 184

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1819

CAS [1140909-48-3]

MF C28H24FN3O5.C4H6O5
MW 635.59

  • Purity: 99%
  • Soluble in DMSO

Cabozantinib S-malate

Description

A orally available and potent inhibitor of multiple receptor tyrosine kinases (RTK), specifically MET and VEGFR2. It also inhibits KIT, FLT3, Tie-2, RET and AXL
Inhibitor of multiple receptor tyrosine kinases, specifically MET and VEGFR2

Chemical name

N-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide (S)-2-hydroxysuccinate

Parent CAS No.

[849217-68-1]
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