產(chǎn)品名稱 WZ 4002
產(chǎn)品貨號(hào) Axon 1506 CAS [1213269-23-8] MF C25H27ClN6O3MW 494.97 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description A mutant-selective EGFR kinase inhibitor against EGFR T790M; a potential agent for some drug-resistant non-small cell lung cancers References Certificates Categories Extra info W Zhou et al. Novel mutant-selective EGFR kinase inhibitors against EGFR T790M. Nature 2009, 462, 1070-1074.? ? Y Sakuma et al. WZ4002, a third-generation EGFR inhibitor, can overcome anoikis resistance in EGFR-mutant lung adenocarcinomas more efficiently than Src inhibitors. Laboratory Investigation 2012, 92, 371-383.? Certificate of Analysis Material Safety Data Sheet Angiogenesis Cell Signaling & Oncology EGFR JAK-STAT RTK class I; EC 2.7.10.1 EGFR kinase inhibitor (T790M specific) Chemical name N-(3-(5-chloro-2-(2-methoxy-4-(4-methylpiperazine-1-yl)phenylamino)pyrimidin-4yloxy)phenyl)acrylam Parent CAS No. [1213269-23-8] Order Size Unit Price Stock 5 mg €70.00 In Stock
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WZ 4002

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1506

CAS [1213269-23-8]

MF C25H27ClN6O3
MW 494.97

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

WZ 4002

Description

A mutant-selective EGFR kinase inhibitor against EGFR T790M; a potential agent for some drug-resistant non-small cell lung cancers
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