產(chǎn)品名稱 VU 0365114
產(chǎn)品貨號 Axon 1943 CAS [1208222-39-2] MF C22H14F3NO3MW 397.35 Purity: 99% Soluble in DMSO and Ethanol Description Selective positive allosteric modulator (PAM) of M5 muscarinic acetylcholine receptor (mAChR), with EC50 = 2.7 μM for M5 and >30 μM for M1–M4 subtypes References Certificates Categories Extra info TM Bridges et al. Heterobiaryl and heterobiaryl ether derived M5 positive allosteric modulators. Bioorg. Med. Chem. Lett. 2010,?20(19), 5617.? ? Structure-activity relationships for a series of M5 muscarinic receptor modulators.?by Rao, Paluri Sai Shantanu, Pharm.D., The University of Toledo, Dissertations & Theses 2011, P/N 3489809.???? Certificate of Analysis Material Safety Data Sheet CNS CHRM5 A18 Selective PAM of M5 mAChR (CHRM5) Chemical name 1-(biphenyl-4-ylmethyl)-5-(trifluoromethoxy)indoline-2,3-dione Parent CAS No. [1208222-39-2] Order Size Unit Price Stock 10 mg €115.00 In Stock
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VU 0365114

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1943

CAS [1208222-39-2]

MF C22H14F3NO3
MW 397.35

  • Purity: 99%
  • Soluble in DMSO and Ethanol

VU 0365114

Description

Selective positive allosteric modulator (PAM) of M5 muscarinic acetylcholine receptor (mAChR), with EC50 = 2.7 μM for M5 and >30 μM for M1–M4 subtypes
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