| 產(chǎn)品名稱 | RS-1 - RAD51-Stimulatory Compound-1 |
| 產(chǎn)品貨號 | Axon 2584 CAS [312756-74-4] MF C20H16Br2N2O3SMW 524.23 Purity: 99% Soluble in DMSO Description Enhancer of CRISPR-based genome editing and homology-directed repair (HDR; RAD51). RS-1 can enhance filament stability, and stimulated hRAD51-mediated homologous strand assimilation (D-loop) activity by at least 5- to 11-fold. RS-1 acts as an allosteric regulator that locks hRAD51 in an active conformation and does so without influencing the active site for ATP hydrolysis. Treatment with RS-1 promoted significant antitumor responses in a mouse model. KEYWORDS:?RS-1 | supplier | RAD51 stimulator | RAD51-Stimulatory Compound-1 | RS1 | CAS [312756-74-4] | DNA-RNA | RAD51 | Stimulator | CRISPR | genome editing | homology-directed repair | HDR | filaments | Cas9 |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
RS-1 - RAD51-Stimulatory Compound-1Axon 2584 CAS [312756-74-4] MF C20H16Br2N2O3S
DescriptionEnhancer of CRISPR-based genome editing and homology-directed repair (HDR; RAD51). RS-1 can enhance filament stability, and stimulated hRAD51-mediated homologous strand assimilation (D-loop) activity by at least 5- to 11-fold. RS-1 acts as an allosteric regulator that locks hRAD51 in an active conformation and does so without influencing the active site for ATP hydrolysis. Treatment with RS-1 promoted significant antitumor responses in a mouse model. KEYWORDS:?RS-1 | supplier | RAD51 stimulator | RAD51-Stimulatory Compound-1 | RS1 | CAS [312756-74-4] | DNA-RNA | RAD51 | Stimulator | CRISPR | genome editing | homology-directed repair | HDR | filaments | Cas9
Enhancer of CRISPR-based genome editing and HDR/RAD51
Chemical name3-(N-benzylsulfamoyl)-4-bromo-N-(4-bromophenyl)benzamide Parent CAS No.[312756-74-4] |
| 產(chǎn)品資料 |
