產(chǎn)品名稱

PKG drug G1 sodium salt

產(chǎn)品貨號(hào)

Axon 2905 CAS [N.A.] MF C13H10N3NaOSMW 279.29 Purity: 98% Soluble in water and DMSO Description PKG drug G1 sodium salt has been shown to induce the oxidative activation of protein kinase G Iα, which in vivo results in dilation of blood vessel and blood pressure lowering; an antihypertensive. The parent molecule is also available as Axon 2232. * Developed and sold in collaboration with KCL (King's College of London). KEYWORDS: PKG drug G1 sodium salt | supplier | PKG Iα inducer | CAS [N.A.] | [374703-78-3] | Non Selective (Phosphorylation Substrates) | PKG | Inducer | Enzymes |?Antihypertension

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產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

PKG drug G1 sodium salt

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2905

CAS [N.A.]

MF C13H10N3NaOS
MW 279.29

Purity: 98%
Soluble in water and DMSO

PKG drug G1 sodium salt

Description

PKG drug G1 sodium salt has been shown to induce the oxidative activation of protein kinase G Iα, which in vivo results in dilation of blood vessel and blood pressure lowering; an antihypertensive.

The parent molecule is also available as Axon 2232.

* Developed and sold in collaboration with KCL (King's College of London).

JR Burgoyne et al. Proof of Principle for a Novel Class of Antihypertensives That Target the Oxidative Activation of PKG Iα (Protein Kinase G Iα). Hypertension. 2017 Sep;70(3):577-586.

Certificate of Analysis
Material Safety Data Sheet

Cardiovascular PKG 2.7.11.12

Inducer of oxidative activation of protein kinase G Iα

Chemical name

Sodium 2-methyl-3-((5-oxo-2-thioxoimidazolidin-4-ylidene)methyl)indol-1-ide

Parent CAS No.

[374703-78-3]

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