產品名稱 STF 118804
產品貨號 Axon 2253 CAS [894187-61-2] MF C25H23N3O4SMW 461.53 Purity: 98% Soluble in DMSO Description Highly specific, next-generation NAMPT inhibitor, that reduces the viability of most B-ALL cell lines with high potency demonstrating IC50 values in the low nanomolar range, and improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia. Additionally, STF 118804 induces leukemia cell apoptosis without antecedent cell cycle arrest, and targets leukemia stem cells. KEYWORDS:?STF 118804 | supplier | NAMPT inhibitor | STF118804 | CAS [894187-61-2] | Nicotinamide D-ribonucleotide | NAD | NAD+ | apoptosis | leukemia | cell cycle | arrest | stem cells
產品價格 現(xiàn)貨詢價，電話：010-67529703
產品規(guī)格
產品品牌 axonmedchem
產品概述
產品詳情

STF 118804

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2253

CAS [894187-61-2]

MF C25H23N3O4S
MW 461.53

  • Purity: 98%
  • Soluble in DMSO

STF 118804

Description

Highly specific, next-generation NAMPT inhibitor, that reduces the viability of most B-ALL cell lines with high potency demonstrating IC50 values in the low nanomolar range, and improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia. Additionally, STF 118804 induces leukemia cell apoptosis without antecedent cell cycle arrest, and targets leukemia stem cells.

KEYWORDS:?STF 118804 | supplier | NAMPT inhibitor | STF118804 | CAS [894187-61-2] | Nicotinamide D-ribonucleotide | NAD | NAD+ | apoptosis | leukemia | cell cycle | arrest | stem cells
產品資料