產(chǎn)品名稱(chēng) AZD 1208
產(chǎn)品貨號(hào) Axon 2795 CAS [1204144-28-4] MF C21H21N3O2SMW 379.48 Purity: 98% Optical purity: optically pure Soluble in DMSO Description AZD 1208 is a pan-Pim kinase inhibitor (IC50 values of 0.4 nM, 5.0 nM and 1.9 nM for Pim-1, Pim-2 and Pim-3, respectively) which does not inhibit FLT3. AZD 1208 treatment resulted in growth inhibition and cell size reduction in AML cell lines including FLT3-WT (OCI-AML-3, KG-1a, MOLM-16) and FLT3-ITD mutated (MOLM-13, MV-4-11). KEYWORDS: AZD 1208 | supplier | PIM inhibitor | AZD1208 | AZD-1208 | CAS [1204144-28-4] | Non Selective (Phosphorylation Substrates) | PIM | Inhibitor | Enzymes | AML
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AZD 1208

Based on 28 reference(s) in Google Scholar 8 10 28

Axon 2795

CAS [1204144-28-4]

MF C21H21N3O2S
MW 379.48

  • Purity: 98%
  • Optical purity: optically pure
  • Soluble in DMSO

AZD 1208

Description

AZD 1208 is a pan-Pim kinase inhibitor (IC50 values of 0.4 nM, 5.0 nM and 1.9 nM for Pim-1, Pim-2 and Pim-3, respectively) which does not inhibit FLT3. AZD 1208 treatment resulted in growth inhibition and cell size reduction in AML cell lines including FLT3-WT (OCI-AML-3, KG-1a, MOLM-16) and FLT3-ITD mutated (MOLM-13, MV-4-11).

KEYWORDS: AZD 1208 | supplier | PIM inhibitor | AZD1208 | AZD-1208 | CAS [1204144-28-4] | Non Selective (Phosphorylation Substrates) | PIM | Inhibitor | Enzymes | AML

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