產(chǎn)品名稱 SB 747651A - SB 747651 tetrahydrochloride
產(chǎn)品貨號 Axon 1897 CAS [N.A.] MF C16H22N8O.4HClMW 488.24 Purity: 98% Soluble in water and DMSO Description Potent MSK inhibitor; In vitro, SB-747651A inhibits MSK1 with an IC50 value of 11 nM; In cells, SB-747651A fully inhibited MSK activity at 5-10 μM.SB-747651A exhibited improved selectivity over H89 and Ro 31-8220 and therefore represents a useful tool to study MSK function in cells References Certificates Categories Extra info S Naqvi et al. Characterization of the cellular action of the MSK inhibitor SB-747651A. Biochem J. 2012, 441(1), 347-357. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology MSK1 MAPK EC 2.7.11.1 Inhibitor of MSK1 Chemical name 4-(1-ethyl-7-((piperidin-4-ylamino)methyl)-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine tetrahydrochloride Parent CAS No. [607372-46-3] Order Size Unit Price Stock 5 mg €120.00 In Stock
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SB 747651A - SB 747651 tetrahydrochloride

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1897

CAS [N.A.]

MF C16H22N8O.4HCl
MW 488.24

  • Purity: 98%
  • Soluble in water and DMSO

SB 747651A

Description

Potent MSK inhibitor; In vitro, SB-747651A inhibits MSK1 with an IC50 value of 11 nM; In cells, SB-747651A fully inhibited MSK activity at 5-10 μM.SB-747651A exhibited improved selectivity over H89 and Ro 31-8220 and therefore represents a useful tool to study MSK function in cells
Inhibitor of MSK1

Chemical name

4-(1-ethyl-7-((piperidin-4-ylamino)methyl)-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine tetrahydrochloride

Parent CAS No.

[607372-46-3]
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