| 產(chǎn)品名稱 | STK16-IN-1 |
| 產(chǎn)品貨號(hào) | Axon 2743 CAS [1223001-53-3] MF C17H12FN3OMW 293.30 Purity: 99% Soluble in DMSO Description STK16-IN-1 is a highly selective ATP-competitive inhibitor which exhibits potent inhibitory activity against STK16 kinase (IC50 value of 0.295 μM). In MCF-7 cells, treatment with STK16-IN-1 results in a reduction in cell number and accumulation of binucleated cells, which can be recapitulated by RNAi knockdown of STK16. Co-treatment of STK16-IN-1 with chemotherapeutics results in a slight potentiation of the antiproliferative effects of the chemotherapeutics. References Certificates Categories Extra info F Liu et al. Discovery of a Highly Selective STK16 Kinase Inhibitor. ACS Chem Biol. 2016 Jun 17;11(6):1537-43. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology EC 2.7.10.2 STK16 ATP-competitive STK16 inhibitor Chemical name 1-(4-Fluoro-3-methylphenyl)-1H-pyrrolo[2,3-h][1,6]naphthyridin-2(7H)-one Parent CAS No. [1223001-53-3] Order Size Unit Price Stock 10 mg €125.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
STK16-IN-1Axon 2743 CAS [1223001-53-3] MF C17H12FN3O
Description
STK16-IN-1 is a highly selective ATP-competitive inhibitor which exhibits potent inhibitory activity against STK16 kinase (IC50 value of 0.295 μM). In MCF-7 cells, treatment with STK16-IN-1 results in a reduction in cell number and accumulation of binucleated cells, which can be recapitulated by RNAi knockdown of STK16. Co-treatment of STK16-IN-1 with chemotherapeutics results in a slight potentiation of the antiproliferative effects of the chemotherapeutics.
ATP-competitive STK16 inhibitor
Chemical name1-(4-Fluoro-3-methylphenyl)-1H-pyrrolo[2,3-h][1,6]naphthyridin-2(7H)-one Parent CAS No.[1223001-53-3] |
| 產(chǎn)品資料 |
