產(chǎn)品名稱

BCI-121

產(chǎn)品貨號

Axon 2735 CAS [432529-82-3] MF C14H18BrN3O2MW 340.22 Purity: 99% Soluble in DMSO Description BCI-121 induces a significant reduction in SMYD3 activity both in vitro and in CRC cells, as suggested by the analysis of global H3K4me2/3 and H4K5me levels. Moreover, BCI-121 inhibits chromatin recruitment and is effective in reducing proliferation in various cancer cell types. KEYWORDS: BCI-121 | supplier | SMYD3 inhibitor? | BCI 121 | BCI121 | CAS [432529-82-3] | Histone | HMTase | Inhibitor | Enzymes

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現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

BCI-121

Based on 2 reference(s) in Google Scholar 8 10 2

Axon 2735

CAS [432529-82-3]

MF C14H18BrN3O2
MW 340.22

Purity: 99%
Soluble in DMSO

BCI-121

Description

BCI-121 induces a significant reduction in SMYD3 activity both in vitro and in CRC cells, as suggested by the analysis of global H3K4me2/3 and H4K5me levels. Moreover, BCI-121 inhibits chromatin recruitment and is effective in reducing proliferation in various cancer cell types.

A Peserico et al. A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth. J Cell Physiol. 2015 Oct;230(10):2447-2460.

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics EC 2.1.1.43 HMTase

Inhibitor of SMYD3

Chemical name

1-(2-(4-Bromophenylamino)-2-oxoethyl)piperidine-4-carboxamide

Parent CAS No.

[432529-82-3]

產(chǎn)品資料