產(chǎn)品名稱

AR 420626

產(chǎn)品貨號(hào)

Axon 2794 CAS [1798310-55-0] MF C21H18Cl2N2O3MW 417.29 Purity: 99% Soluble in DMSO Description AR 420626 is an allosteric FFA3 (GPR41) receptor agonist (pEC50 value of 5.74) which enhances mucosal defenses and prevents NSAID-induced enteropathy via the GLP-2 pathway in rats. KEYWORDS: AR 420626 | supplier | GPR41 agonist | AR420626 | AR-420626 | CAS [1798310-55-0] | FFA | GPR41 | Agonist | Receptors | FFA3 | GLP-2

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

AR 420626

Based on 2 reference(s) in Google Scholar 8 10 2

Axon 2794

CAS [1798310-55-0]

MF C21H18Cl2N2O3
MW 417.29

Purity: 99%
Soluble in DMSO

AR 420626

Description

AR 420626 is an allosteric FFA3 (GPR41) receptor agonist (pEC50 value of 5.74) which enhances mucosal defenses and prevents NSAID-induced enteropathy via the GLP-2 pathway in rats.

KEYWORDS: AR 420626 | supplier | GPR41 agonist | AR420626 | AR-420626 | CAS [1798310-55-0] | FFA | GPR41 | Agonist | Receptors | FFA3 | GLP-2

BD Hudson et al. Complex pharmacology of novel allosteric free fatty acid 3 receptor ligands. Mol Pharmacol. 2014 Aug;86(2):200-10.

H Said et al. FFA3 Activation Stimulates Duodenal Bicarbonate Secretion and Prevents NSAID-Induced Enteropathy via the GLP-2 Pathway in Rats. Dig Dis Sci. 2017 Aug;62(8):1944-1952.

Certificate of Analysis
Material Safety Data Sheet

Diabetes & Metabolism Pain & Inflammation A11 GPR41

GPR41 receptor agonist (FFA3)

Chemical name

N-(2,5-Dichlorophenyl)-4-(furan-2-yl)-2-methyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxamide

Parent CAS No.

[1798310-55-0]

產(chǎn)品資料