產(chǎn)品名稱

M 24 - M024/C21

產(chǎn)品貨號

Axon 1969 CAS [477775-14-7] MF C23H29N3O4S2MW 475.62 Purity: 98% Soluble in DMSO Description First reported non-peptide selective AT2 receptor agonist (Ki 0.4nM and 10.000 nM for AT2 and AT1 respectively). M 24 shows a bioavailability of 20-30% after oral administration and a half-life estimated to 4 h in rat. Note:

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產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

M 24 - M024/C21

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1969

CAS [477775-14-7]

MF C23H29N3O4S2
MW 475.62

Purity: 98%
Soluble in DMSO

M 24

Description

First reported non-peptide selective AT2 receptor agonist (Ki 0.4nM and 10.000 nM for AT2 and AT1 respectively). M 24 shows a bioavailability of 20-30% after oral administration and a half-life estimated to 4 h in rat.

Note:?This item is currently suspended due to the request of the developer. You may request a quotation for contract research synthesis. Please contact?us?for conditions and more detailed information.

Y Wan et al. Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist. J. Med. Chem. 2004, 47, 5995-6008.

AMS Murugaiah et al. From the First Selective Non-Peptide AT2 Receptor Agonist to Structurally Related Antagonists. J. Med. Chem. 2012, 55, 2265?227.

Certificate of Analysis
Material Safety Data Sheet

Cardiovascular Endocrinology A3 Angiotensin (AT)

First non-peptide selective AT2 receptor agonist

Chemical name

butyl 3-(4-((1H-imidazol-1-yl)methyl)phenyl)-5-isobutylthiophen-2-ylsulfonylcarbamate

Parent CAS No.

[477775-14-7]

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