產(chǎn)品名稱 JNJ 63533054
產(chǎn)品貨號 Axon 2569 CAS [1802326-66-4] MF C17H17ClN2O2MW 316.78 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Potent, brain-penetrant, orally active, and selective agonist of hGPR139 (EC50 value 16 nM; 138% of max) with no inhibitory effect on CYP450. A useful tool for exploring GPR139 pharmacology, especially when combined with NCRW0005-F05 (Axon 2609), the first potent GPR139 antagonist available. KEYWORDS: JNJ 63533054 | supplier | GPR139 agonist | JNJ63533054 | CAS [1802326-66-4] | GPR139 | Agonist | GPCR | orphan | CNS | diabetes | metabolic | brain | tool | central nervous system
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JNJ 63533054

Based on 5 reference(s) in Google Scholar 9 10 5

Axon 2569

CAS [1802326-66-4]

MF C17H17ClN2O2
MW 316.78

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in DMSO

JNJ 63533054

Description

Potent, brain-penetrant, orally active, and selective agonist of hGPR139 (EC50 value 16 nM; 138% of max) with no inhibitory effect on CYP450. A useful tool for exploring GPR139 pharmacology, especially when combined with NCRW0005-F05 (Axon 2609), the first potent GPR139 antagonist available.

KEYWORDS: JNJ 63533054 | supplier | GPR139 agonist | JNJ63533054 | CAS [1802326-66-4] | GPR139 | Agonist | GPCR | orphan | CNS | diabetes | metabolic | brain | tool | central nervous system
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