加拿大cellscale生物組織材料機械力te性測試分析儀

型號:內(nèi)詳
價格:請致電:010-67529703
品牌:cellscale

CellScale的生物反應器為細胞和組織及其它材料對機械刺激的反應提供了深入的洞察。cellscale系統(tǒng)針對高通量、實時成像、3D支架使用和多模式刺激進行了化。CellScale在開發(fā)定制解決方案方面擁有豐富的經(jīng)驗,效果屢超客戶預期。

機械測試系統(tǒng)。

在CellScale,我們的測試系統(tǒng)從頭到尾進行了化,以表征生物材料的力學性能。環(huán)境艙和成像實現(xiàn)了完整的系統(tǒng)功能,省去了后顧之憂。 能滿足從微尺度壓縮到雙軸拉伸的需求,CellScale的系統(tǒng)能提供值得信賴的尖端數(shù)據(jù)。



一、BioTester雙軸材料

專為生物材料而打造的一套設備齊的雙軸測試系統(tǒng)

由于其定向取向的微觀結(jié)構(gòu),雙軸測試對于理解生物材料的機械性能而言是至關重要的。BioTester系統(tǒng)的設計使雙軸測試變得簡單,使用戶可以專注于結(jié)果而不是測試本身。

主要勢

  • 4個高性能的執(zhí)行機構(gòu),帶有直列加載傳感器
  • 使用基于圖像應變測量工具的高分辨率CCD成像
  • 包括專利BioRakes在內(nèi)的多種附著選項,可快速可靠地安裝樣品
  • 集成溫控介質(zhì)浴
  • 功能齊的用戶界面軟件,可進行實時反饋的簡單、循環(huán)、松弛和多模式測試


試樣和安裝

BioRake樣品安裝系統(tǒng)使用了CellScale專利技術(shù)的附著軟組織和生物材料的方法。

每根尖齒都經(jīng)過電化學銳化,可以輕松刺穿硬和脆弱的組織樣本。每套都永久性地連接到一個共同的基座,可以同時刺穿鎖有20個連接點。磁力安裝的BioRakes便于清潔或更換,可以實現(xiàn)BioRake、平衡滑輪和夾具安裝系統(tǒng)之間的輕松轉(zhuǎn)換。

進行測試時,使用手動升降機構(gòu)將樣本定位并升高到位,并施加壓力以將鉤子插入組織中。樣品因此可以在幾秒鐘內(nèi)安裝好并做好分析準備。安裝一氣呵成、準確易操作。

BioRakes的齒間距從0.7毫米到2.2毫米不等,以適應從3到15毫米大小的標本。

BioRake樣品安裝系統(tǒng)

平衡滑輪樣品安裝系統(tǒng)提供了CellScale在雙軸測試過程中確保零剪切應力的附著方法。

兩個雙端定制縫合鉤被用來在樣品的每一側(cè)上創(chuàng)建4個附著點。兩級不銹鋼滑輪機構(gòu)確保在測試過程中每根縫線保持相同的張力。

滑輪機構(gòu)采用磁性安裝方式,便于拆卸清潔,并使BioRake、平衡滑輪和夾具安裝系統(tǒng)之間輕松過渡。

平衡滑輪安裝系統(tǒng)

夾具樣品安裝系統(tǒng)提供了CellScale失敗測試的附著方法。

使用十字形試樣可以讓比基礎材料更弱的附著位置遠離試樣的測量區(qū)域移動。夾具讓樣品可以很容易地加載并且牢固地就位。

不銹鋼夾緊機構(gòu)安裝在與其他附著系統(tǒng)相同的支架上,以便在BioRake、平衡滑輪和夾具安裝系統(tǒng)之間快速簡單的轉(zhuǎn)換。

還可以進行定制夾具設計,以適應您的組織對夾緊力和夾緊表面的要求。

夾具安裝系統(tǒng)


軟件

BioTester的設置、操作和數(shù)據(jù)收集軟件模塊讓標準或定制測試規(guī)程的執(zhí)行變得容易。

測試參數(shù)(如位移量、持續(xù)時間和數(shù)據(jù)/圖像采集速率)以表格格式指定,以便快速訪問和修改。位移和受力測試都可以針對每個軸立指定。一旦建立了協(xié)議,就可以使用模板系統(tǒng)快速重新加載所需的測試參數(shù)。

軟件界面在測試設置期間向用戶提供實時成像和當前的力、位置和溫度的信息。在測試運行時,軟件提供實時結(jié)果圖形和實時視頻饋送,以方便用戶監(jiān)視測試進度。

如果詢問使用我們設備的用戶,他們會很快告訴您這個軟件包是多么的直觀和有用。

 

BioRake樣品安裝系統(tǒng)


雙軸測試的很大一部分是理解和解釋收集到的數(shù)據(jù)。

BioTester包含一個圖像分析軟件模塊,可用于查看和分析測試圖像,提供有價值的定量和定性信息。該模塊可以用來導出用于演示目的.avi視頻或帶有數(shù)據(jù)疊加層的圖像。

BioTester包含一個高分辨率的相機,在測試過程中可以很好地觀察樣品。所收集的圖像(按用戶指定的頻率)自動和力位移數(shù)據(jù)進行時間關聯(lián),以便軟件模塊可以將鎖有的測試信息供用戶選用。

軟件模塊的圖像跟蹤功能可以快速輕松地分析測試圖像,以確定樣本表面上一個或多個點的平面內(nèi)運動。這個跟蹤信息提供了直接的標本應變測量,而不依靠由夾點運動計算的應變。通過追蹤多點組成的網(wǎng)格,可以研究樣品不同區(qū)域的應變。


平衡滑輪安裝系統(tǒng)


二、UniVert單軸拉伸、壓縮和扭力測試分析

隨時隨地進行您需要的機械測試

UniVert是各種機械測試應用的里想選擇,它的占地面積小,價格合理,使用戶可以隨時隨地進行測試。易于使用的軟件和可互換的組件使得系統(tǒng)wu需大量的培訓或督導即可使用。

該系統(tǒng)能夠承受高達200N的拉伸、壓縮和彎曲測試。各種夾具和固定裝置可用于適應不同的標本和測試模式。

主要勢

  • 小體量即可進行質(zhì)量好、性價比高的測試
  • 夾具和加載傳感器的變化易于操作,可以適應各種用途。
  • 使用基于圖像的應變測量工具,可實現(xiàn)高分辨率CCD成像(可選)
  • 功能齊的用戶界面軟件,可通過實時反饋進行簡單、循環(huán)、松弛和多模式測試
參數(shù):
外形尺寸 22 X 22 X 54cm
重量 8kg
力的大小 200N
可用的加載傳感器 10, 20, 50, 100, 200N
力的準確性 加載傳感器容量的0.2%
大夾點分離 140mm
大速度 20mm/s
大循環(huán)頻率 2Hz
大數(shù)據(jù)速率 100Hz

三、MicroSquisher壓縮、拉伸、彎曲、壓痕和剪切測試

MicroSquisher是一個微型機械測試系統(tǒng),可以做別人所不能做之事。更小的標本,更好的解像力,更容易的測試設置和j佳的視覺效果。應用包括小組織樣品,水凝膠微球,細胞球體和工程化組織生長基質(zhì)。

主要勢

  • 壓縮、拉伸、彎曲、壓痕和剪切測試的測試模式
  • 0.1μm分辨率的高精度壓電執(zhí)行器
  • 解像力降至10nN
  • 高分辨率的CCD成像
  • 集成溫控介質(zhì)浴
  • 功能齊的用戶界面軟件,可進行實時反饋的簡單、循環(huán)、松弛和多模式測試

試樣和安裝

平行板壓縮
樣品:300μm水凝膠微球(30KPa)
峰力:20mN

懸臂彎
試樣:20μm厚、4mm寬箔帶(70MPa)
峰力:3mN

平行板壓縮
標本:直徑2毫米的水凝膠圓柱體(12KPa)
峰力:20mN

球形壓痕
樣品:1.5mm直徑壓頭壓入水凝膠(2KPa)
峰力: 12mN

彎曲引起的拉伸
標本:蜘蛛絲
峰力:2mN

穿刺附著拉伸
樣品:3.5mm寬,1.5mm厚的水凝膠(0.5KPa)
峰力:1.4mN

四、UStretch用于生物材料的多功能單軸臺式機械測試儀


UStretch不僅限于大型試樣夾點的干燥垂直測試。它還可以在溫控或非溫控的介質(zhì)槽內(nèi)進行垂直和水平測試。 他們的系統(tǒng)還有各種各樣的樣品附件,包括螺桿驅(qū)動夾具、彈簧夾具和多點刺穿夾具。

主要勢

  • 帶有直列式加載傳感器的高性能執(zhí)行器
  • 使用基于圖像的應變測量工具,擁有高分辨率CCD成像
  • 有包括專利產(chǎn)品BioRakes在內(nèi)的多種附件選件,可快速可靠地安裝樣品
  • 集成溫控介質(zhì)浴
  • 功能齊的用戶界面軟件,可通過實時反饋進行簡單、循環(huán)、松弛和多模式測試

試樣和安裝

BioRake

獲得專利的BioRake附著系統(tǒng)可以使標本快速準確地安裝。

BioRake樣品安裝系統(tǒng)

機械夾點

機械夾點附著系統(tǒng)有利于實現(xiàn)更大的力量和進行樣本失敗測試。

機械夾點

軟件

集成的軟件可以輕松指定簡單或復雜的測試規(guī)程。測試規(guī)程可以保存和修改。實時的力量和位移圖形有助于測試驗證。

UStretch軟件與BioTester 軟件構(gòu)建在同一個平臺上。 .

Ustretch 軟件

成像系統(tǒng)

可選的成像系統(tǒng)和分析軟件可以對圖像進行分析,以驗證樣品的應變和應變的均勻性。

Ustretch 軟件

應用文獻:


Instrument

Year

Title

Author

Link

BioTester

2018

Biaxial mechanical behavior of bovine saphenous venous valve leaflets

J. Lu, H-Y S. Huang

View Article

UniVert

2018

Mechanical Strength Of Nafion®/ZrO2 Nano-Composite Membrane

R. Sigwadi, F. Nemavhola, S. Dhlamini, T. Mokrani

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MechanoCulture B1

2018

Role of boundary conditions in determining cell alignment in response to stretch

K. Chen, A. Vigliotti, M. Bacca, R. M. McMeeking, V.S. Dashpande, J.W. Holmes

View Article

BioTester

2018

Prevalence of Calcification in Human Femoropopliteal Arteries and its Association with Demographics, Risk Factors, and Arterial Stiffness

A. Kamenskiy, W. Poulson, S. Sim, A. Reilly, J. Luo, J. MacTaggart

View Article

BioTester

2018

Comparison of corneal biomechanics after myopic small-incision lenticule extraction compared to LASIK: an ex vivo study

A.J. Kanellopoulos

View Article

UniVert

2018

Three-Dimensional Printing of Bisphenol A-Free Polycarbonates

W. Zhu, S-H. Pyo, S. You, C. Yu, J. Alido, J. Liu, Y. Leong, S. Chen

View Article

BioTester

2018

Dehiscence of patch augmentation of a left-sided atrioventricular valve related to strenuous isometric exercise: Case report and failure analysis

P.E. Hammer, C.W. Baird, P.J. del Nido, G.R. Marx

View Article

BioTester

2018

Puncturing of lyophilized tissue engineered vascular matrices enhances the efficiency of their recellularization

A.A. Ksiazek, L. Frese, P.E. Dijkman, B. Sanders, S. E. Motta, B. Weber, S.P. Hoerstrup

View Article

BioTester

2018

Biomechanical evaluation of a personalized external aortic root support applied in the Ross procedure

J. Vastmans, H. Fehervary, P. Verbrugghe, T. Verbelen, E. Vanderveken, J. Vander Sloten, T. Treasure, F. Rega, N. Famaey

View Article

BioTester

2018

Polydopamine as sizing on carbon fiber surfaces for enhancement of epoxy laminated composites

W. Han, H-P. Zhang, J. Tavakoli, J. Campbell, Y. Tang

View Article

BioTester

2018

Comparison of in vivo vs. ex situ obtained material properties of sheep common carotid artery

M. Smoljkic, P. Verbrugghe, M. Larsson, E. Widman, H. Fehervary, J. D'hooge, J. Vander Sloten, N. Famaey

View Article

BioTester

2018

Soy Protein/Cellulose Nanofiber Scaffolds Mimicking Skin Extracellular Matrix for Enhanced Wound Healing

S. Ahn, C.O. Chantre, A.R. Gannon, J.U. Lind, P.H. Campbell, T. Grevesse, B.B. O'Conner, K.K. Parker

View Article

BioTester

2018

New findings confirm the viscoelastic behaviour of the inter-lamellar matrix of the disc annulus fibrosus in radial and circumferential directions of loading

J. Tavakoli, J.J. Costi

View Article

Ustretch

2018

Self-assembled Collagen-Fibrin Hydrogel Reinforces Tissue Engineered Adventitia Vessels Seeded with Human Fibroblasts

B. Patel, Z. Xu, C. Pinnock, L.S. Kabbani, M.T. Lam

View Article

BioTester

2018

3D printed, controlled release, tritherapeutic tablet matrix for advanced anti-HIV-1 drug delivery

M. Siyawamwaya, L.C. du Toit, P. Kumar, Y.E. Choonara, P.P.P.D Kondiah, V. Pillay

View Article

MicroSquisher

2018

Acrylate-based materials for heart valve scaffold engineering

R. Santoro, S. Venkateswaran, F. Amandeo, R. Zhang, M. Brioschi, A. Callanan, M. Agrifoglio, C. Banfi, M. Bradley, M. Pesce

View Article

BioTester

2018

Computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model

M.Y. Emmert, B.A. Schmitt, S. Loerakker, B. Sanders, H. Spriestersbach,, E.S. Fioretta, L. Bruder, K. Brakmann, S.E. Motta, V. Lintas, P.E. Dijkman, L. Frese, F. Berger, F.P.T. Baaijens, S.P. Hoerstrup

View Article

UniVert

2018

Fabrication of functionalized citrus pectin/silk fibroin scaffolds for skin tissue engineering.

S. Tukkan, D. Atila, A. Akdaq, A. Tezcaner

View Article

UniVert

2018

Rapid continuous 3D printing of customizable peripheral nerve guidance conduits

W. Zhu, K.R. Tringale, S.A. Woller, S. You, S. Johnson, H. Shen, J. Schimelman, M. Whitney, J. Steinauer, W. Xu, T.L. Yaksh, Q.T. Nguyen, S.Chen

View Article

MicroSquisher

2018

A Microvascularized Tumor-mimetic Platform for Assessing Anti-cancer Drug Efficacy

S. Pradhan, A.M. Smith, C.J. Garson, I. Hassani, W.J. Seeto, K. Pant, R.D. Arnold, B. Prabhakarpandian, E.A. Lipke

View Article

UniVert

2017

A highly deformable conducting traces for printed antennas and interconnects: silver/fluoropolymer composite amalgamated by triethanolamine

A. Kumar, H. Saghlatoon, T-G. La, M. M. Honari, H. Charaya, H.A. Damis, R. Mirzavand, P. Mousavi, H-J. Chung

View Article

MicroSquisher

2017

A three-dimensional spheroidal cancer model based on PEG-fibrinogen hydrogel microspheres

S.Pradhan, J. M. Clary, D. Seliktar, E. A. Lipke

View Article

BioTester

2017

Biaxial experimental and analytical characterization of a dielectric elastomer

A. Helal, M. Doumit, R. Shaheen

View Article

BioTester

2017

Biaxial mechanical properties of bovine jugular venous valve leaflet tissues

H-Y. S. Huang, J. Lu

View Article

BioTester

2017

Comparison of Femoropopliteal Artery Stents Under Axial and Radial Compression, Axial Tension, Bending, and Torsion Deformations

K. Maleckis, P. Deegan, W. Poulson, C. Sievers, A. Desyatova, J. MacTaggart, A. Kamenskiy

View Article

BioTester

2017

Constitutive modeling of human femoropopliteal artery biaxial stiffening due to aging and diabetes

A. Desyatova, J. MacTaggart, A. Kamenskiy

View Article

BioTester

2017

Constitutive modeling of jugular vein-derived venous valve leaflet tissues

N. Kaul, H-Y. S. Huang

View Article

MicroSquisher

2017

Decellularized adipose tissue microcarriers as a dynamic culture platform for human adipose-derived stem/stromal cell expansion

C. Yu, A. Kornmuller, C. Brown, T. Hoare, L.E. Flynn

View Article

BioTester

2017

Design and characterization of a hyperelastic tubular soft composite

R. Shaheen, M. Doumit, A. Helal

View Article

MicroSquisher

2017

Encapsulation of Equine Endothelial Colony Forming Cells in Highly Uniform, Injectable Hydrogel Microspheres for Local Cell Delivery

W.J. Seeto, Y. Tian, R.L. Winter, F.J. Caldwell, A.A. Wooldridge, E.A. Lipke

View Article

BioTester

2017

In situ heart valve tissue engineering using a bioresorbable elastomeric implant – From material design to 12 months follow-up in sheep

J. Kluin, H. Talacua, A.I.P.M. Smits, M. Y. Emmert, M.C.P. Brugmans, E.S. Fioretta, P.E. Dijkman, S.H.M. Sontjens, R.Duijvelshoff, S. Dekker, M.W.J.T. Janssen-van den Broek, V. Lintas, A. Vink, S.P. Hoerstrup, H.M. Janssen, P.Y.W. Dankers, F.P.T. Baaijens, C.V.C. Bouten

View Article

BioTester

2017

JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement

A.K. Capulli, M.Y. Emmert, F.S. Pasqualini, D. Kehl, E. Caliskan, J.U. Lind, S. P. Sheehy, S.J. Park, S. Ahn, B. Weber, J.A. Goss, S.P Hoerstrup, K.K. Parker

View Article

BioTester

2017

Limb flexion-induced twist and associated intramural stresses in the human femoropopliteal artery

A. Desyatova, W. Poulson, P. Deegan, C. Lomneth, A. Seas, K. Maleckis, J. MacTaggart, A. Kamenskiy

View Article

MechanoCulture T6

2017

Living nanofiber yarn-based woven biotextiles for tendon tissue engineering using cell tri-culture and mechanical stimulation

S. Wu, Y. Wang, P.N. Streubel, B. Duan

View Article

MechanoCulture FX

2017

Mechanical and signaling roles for keratin intermediate filaments in the assembly and morphogenesis of mesendoderm tissue at gastrulation

P.R. Sonavane, C. Wang, B. Dzamba, G.F. Weber, A. Periasamy, D.W. DeSimone

View Article

BioTester

2017

Mechanically Robust Electrospun Hydrogel Scaffolds Crosslinked via Supramolecular Interactions

B.B. Mollet, S. Spaans, P.G. Fard, N.A.M. Bax, C.V.C. Bouten, P.Y.W. Dankers

View Article

MicroSquisher

2017

Microfluidic production of degradable thermoresponsive poly(N-isopropylacrylamide)-based microgels

D. Sivakumaran, E. Mueller, T. Hoare

View Article

BioTester

2017

Nondestructive mechanical characterization of developing biological tissues using inflation testing

P.J.A. Oomen, M.A.J. van Kelle, C.W.J. Oomens, C.V.C. Bouten, S. Loerakker

View Article

BioTester

2017

On the influence of wall calcification and intraluminal thrombus on prediction of abdominal aortic aneurysm rupture

H.E. Barrett, E.M. Cunnane, H. Hidayat, J.M. O'Brien, M.A. Moloney, E.G. Kavanagh, M.T. Walsh

View Article

BioTester

2017

Paraspinal Muscle Passive Stiffness Remodels in Direct Response to Spine Stiffness: A Study Using the ENT1-Deficient Mouse

K. Gsell, D. Zwambag, D.E. Fournier, C.A. Seguin, S.H.M. Brown

View Article

MicroSquisher

2017

PEG-fibrinogen hydrogels for three-dimensional breast cancer cell culture

S. Pradhan, I. Hassani, W.J. Seeto, E.A. Lipke

View Article

MicroSquisher

2017

Polysaccharide Hydrogels Support the Long-Term Viability of Encapsulated Human Mesenchymal Stem Cells and Their Ability to Secrete Immunomodulatory Factors

F. Hached, C. Vinatier, P-G. Pinta, P. Hulin, C. Le Visage, P. Weiss, J. Guicheux, A. Billon-Chabaud, G. Grimandi

View Article

MicroSquisher

2017

Pullulan microbeads/Si-HPMC hydrogel injectable system for the sustained delivery of GDF-5 and TGF-β1: new insight into intervertebral disc regenerative medicine

N. Henry, J. Clouet, A. Fragale, L.Griveau, C. Chedevile, J. Veziers, P. Weiss, J. Le Bideau, J. Guicheaux, C. Le Visage

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MicroSquisher

2017

Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy

D. Gillies, W. Gamal, A. Downes, Y. Reinwald, Y. Yang, A.J. El Haj, P.O. Bagnaninchi

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UniVert

2017

Self-reinforcing graphene coatings on 3D printed elastomers for flexible radio frequency antennas and strain sensors

X. Li, M.M. Honari, Y. Fu, A. Kumar, H. Saghlatoon

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MechanoCulture FX

2017

Tenogenic phenotype maintenance and differentiation using macromolecular crowding and mechanical loading

D. Gaspar, A. Pandit, D. Zeugolis

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BioTester

2017

Tensile behaviour of individual fibre bundles in the human lumbar anulus fibrosus

D.T. Pham, J.G. Shapter, J.J. Costi

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MicroSquisher

2017

The physical basis of coordinated tissue spreading in zebrafish gastrulation

H. Morita, S. Grigolon, M. Bock, S.F.G. Krens, G. Salbreux, C-P. Heisenberg

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MicroSquisher

2017

The role of adhesion junctions in the biomechanical behaviour and osteogenic differentiation of 3D mesenchymal stem cell spheroids

F.E. Griffin, J. Schiavi, T.C. McDevitt, J.P. McGarry, L.M. McNamara

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BioTester

2017

Urinary Bladder Versus Gastrointestinal Tissue: a Comparative Study of Their Biomechanical Properties for Urinary Tract Reconstruction

N.F. Davis, J.J.E. Mulvihill, S. Mulay, E.M. Cunnane, D.M. Bolton, M.T. Walsh

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BioTester

2016

A comparison between porcine, ovine, and bovine intervertebral disc anatomy and single lamella annulus fibrosis tensile properties

L.A. Monaco, S.J. DeWitte-Orr, D.E. Gregory

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BioTester

2016

Acute pergolide exposure stiffens engineered valve interstitial cell tissues and reduces contractility in vitro

A.K. Capulli, L.A. MacQueen, B.B. O'Conner, S. Dauth, K.K. Parker

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MechanoCulture T6

2016

Additive manufacturing of a photo-cross-linkable polymer via direct meld electrospinning writing for producing high strength structures

F. Chen, G. Hochleitner, T. Woodfield, J. Groll, P. Dalton, B.G. Amsden

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BioTester

2016

Age-Dependent Changes in Geometry, Tissue Composition and Mechanical Properties of Fetal to Adult Cryopreserved Human Heart Valves

D. van Geeman, A.L.F. Soares, P.J.M. Oomen, A. Dressen-Mol, M.W.J.T. Janssen-van den Broek, A.J. van den Bogaerdt, J.J.C. Bogers, M-J. T.H. Goumans, F.P.T. Baaijens, C.V.C. Bouten

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MicroSquisher

2016

An Injectable Hydrogel Prepared Using a PEG/Vitamin E Copolymer Facilitating Aqueous-Driven Gelation

J. Zhang, B. Muirhead, M. Dodd, L. Liu, N. Mangiacotte, T. Hoare, S. Sheardown

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BioTester

2016

Are adipose-derived stem cells cultivated in human platelet lysate suitable for heart valve tissue engineering

L. Frese, T. Sasse, B. Sanders, F.P.T. Baaijens, G.M. Beer, S.P. Hoerstrup

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BioTester

2016

Biaxial quantification of deep layer transverse carpal ligament elastic properties by sex and region

B. Mathers, A. Agur, M. Oliver, K. Gordon

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BioTester

2016

Biomechanical Characterization of Ascending Aortic Aneurysms

M. Smoljkic, H. Fehervary, P. Van den Bergh, A. Jorge-Penas, L. Kluyns, S. Dymarkowski, P. Verbrugghe, B. Meuris, J. Vander Sloten, N. Famaey

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BioTester

2016

Biomechanical properties and microstructure of heart chambers: a paired comparison study in an ovine model

S. Javani, M. Gordon, A.N. Azadani

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BioTester

2016

Characterization of three-dimensional anisotropic heart valve tissue mechanical properties using inverse finite element analysis

M. Abbasi, M.S. Barakat, K. Vanhidkhah, A.N. Azadani

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BioTester

2016

Constitutive description of human femoropopliteal artery aging

A. Kamenskiy, A. Seas, P. Deegan, W. Poulson, E. Anttila, S. Sim, A. Desyatova, J. MacTaggart

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MicroSquisher

2016

Delivery of Human Adipose Stem Cells Spheroids into Lockyballs

K.R. Silva, R.A. Rezende, F.D.A.S. Pereira, P. Gruber, M.P. Stuart, A. Ovsianikov, K. Brakke, V. Kasyanov, J.V.L. da Silva, J.M. Granjeiro, L.S. Baptista, V. Mironov

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BioTester

2016

Deposition of a hydrophilic nanocomposite-based coating on a silicone hydrogel through a laser process to minimize UV exposure and bacterial contamination

G. Huang, W. H. Tse, J. Zhang

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UniVert

2016

Development of an infusion bioreactor for the accelerated preparation of decellularized letal muscle scaffolds

B. M. Kasukonis, J.T. Kim, T.A. Washington, J.C. Wolchok

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MicroSquisher

2016

Direct Production of Human Cardiac Tissues by Pluripotent Stem Cell Encapsulation in Gelatin Methacryloyl

P. Kerscher, J.A. Kaczmarek, S.E. Head, M. Brazel, W. Seeto, S. Bhattacharya, J. Kim, V. Suppiramaniam, E.A. Lipke

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BioTester

2016

Improved Geometry of Decellularized Tissue Engineered Heart Valves to Prevent Leaflet Retraction

B. Sanders, S. Loerakker, E.S. Fioretta, D.J.P. Bax, A. Driessen-Mol, S.P. Hoerstrup, F.P.T. Baaijens

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BioTester

2016

Inflation and bi-axial tensile testing of healthy porcine carotid arteries

R.W. Boekhoven, M.F.J. Peters, M.C.M. Rutten, M.R. van Sambeek, F.N. van de Vosse, R.G.P Lopata

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UniVert

2016

Material Properties from Air Puff Corneal Deformation by Numerical Simulations on Model Corneas

N. Bekesi, C. Dorronsoro, A. de la Hoz, S. Marcos

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MicroSquisher

2016

Mineral particles modulate osteo-chondrogenic differentiation of embryonic stem cell aggregates

Y. Wang, X. Yu, C. Baker, W.L. Murphy, T.C. McDevitt

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BioTester

2016

Modulation of collaen fiber orientation by strain-controlled enzymatic degradation

S. Ghazanfari, A. Dressen-Mol, C.V.C. Bouten, F.P.T. Baaijens

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BioTester

2016

Nanocomposited coatings produced by laser-assisted process to prevent silicone hydrogels from protein fouling and bacterial contamination

G. Huang, Y. Chen, J. Zhang

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BioTester

2016

Patient Specific Vascular Benchtop Models for Development and Validation of Medical Devices for Minimally Invasive Procedures

M. Kvasnytsia, N. Famaey, M. Bohm, E. Verhoelst

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BioTester

2016

Peak stress in the annulus fibrosis under cyclic biaxial tensile loading

C.E. Gooyers, J.P. Callaghan

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MicroSquisher

2016

PEG-fibrinogen Hydrogels for Three-dimensional Breast Cancer Cell Culture

S. Pradhan, I. Hassani, W.J. Seeto, E. A. Lipke

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BioTester

2016

Phototactic guidance of a tissue-engineered soft-robotic ray

S-J. Park, M. Gazzola, K.S. Park, S. Park, V. Di Santo, E.L Blevins, J.U. Lind, P.H. Campbell, S. Dauth, K.K. Parker

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BioTester

2016

Planar biaxial testing of heart valve cusp replacement biomaterials: Experiments, theory and material constants

M.R. Labrosse, R. Jafar, J.Ngu, M. Boodhwani

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BioTester

2016

Planar biaxial testing of soft biological tissue using rakes: A critical analysis of protocol and fitting process

H. Fehervary, M. Smoljkic, J.Vander Sloten, N. Famaey

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BioTester

2016

Production of Synthetic, Para-Aramid and Biopolymer Nanofibers by Immersion Rotary Jet-Spinning

G.M. Gonzalez, L.A. MacQueen, J.U. Lind, S.A. Fitzgibbons, C. O. Chantre, I. Huggler, H.M. Golecki, J.A. Goss, K.K. Parker

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BioTester

2016

Quantification of Coupled Stiffness and Fiber Orientation Remodeling in Hypertensive Rat Right-Ventricular Myocardium Using 3D Ultrasound Speckle Tracking with Biaxial Testing

D.W. Park, A. Sebastiani, C.H. Yap, M.A. Simon, K. Kim

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MicroSquisher

2016

Reactive eletrospinning of degradable poly(oligoethylene glycol methacrylate)-based nanofibrous hydrogel networks

F. Xu, H. Sheardown, T. Hoare

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BioTester

2016

The aging disc: using an ovine model to examine age-related differences in the biomechanical properties of the intralamellar matrix of single lamellae

D.M. Stewart, L.A. Monaco, D.E. Gregory

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BioTester

2016

The choice of a constitutive formulation for modeling limb flexion-induced deformations and stresses in the human femoropopliteal arteries of different ages

A. Desyatova, J. MacTaggart, W. Poulson, P. Deegan, C. Lomneth, A. Sandip, A. Kamenskiy

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BioTester

2016

The Effect of Local Hydration Environment on the Mechanical Properties and Unloaded Temporal Changes of Isolated Porcine Annular Samples

K.M. Gruevski, C.E. Gooyers, T. Karakolis, J.P. Callaghan

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UniVert

2016

The global mechanical properties and multi-scale failure mechanics of heterogeneous human stratum corneum

X. Liu, J. Cleary, G.K. German

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BioTester

2015

Adipose derived tissue engineered heart valve

L. Frese, B. Sanders, G.M. Beer, B. Weber, A. Driessen-Mol, F.P.T. Baaijens, S.P. Hoerstrup

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BioTester

2015

Biaxial stress relaxation of semilunar heart valve leaflets during simulated collagen catabolism: effects of collagenase concentration and equibiaxial strain state

S. Huang, H.-Y. S. Huang

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BioTester

2015

Building a better infarct: Modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction

A.P. Voorhees, K.Y. DeLeon-Pennell, Y. Ma, G. V. Halade, A. Yabluchanskiy, R. Padmanabhan, E. Flynn, C.A. Cates, M.L. Lindsey, H.-C. Han

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MicroSquisher

2015

Burr-like, laser-made 3D microscaffolds for tissue spheroid encagement

P. Danilevicius, R.A. Rezende, F.D.A.S. Pereira, A. Selimis, V. Kasyanov, P.Y. Noritomi, J.V.L. da Silva, M.Chatzinikolaidou, M. Farsari, V. Mironov

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BioTester

2015

Corneal collagen cross-linking combined with simulation of femtosecond laser-assisted refractive lens extraction: an ex vivo biomechanical effect evaluation

A.J. Kanellopoulos, M.A. Kontos, S. Chen, G. Asimellis

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BioTester

2015

Development of a biological scaffold engineered using the extracellular matrix secreted by letal muscle cells

S.A. Hurd, N.M. Bhatti, A.M. Walker, B.M. Kasukonis, J.C. Wolchok

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UniVert

2015

Development of a biological scaffold engineered using the extracellular matrix secreted by letal muscle cells

S. A. Hurd, N.M. Bhatti, A.M. Walker, B.M. Kasukonis, J.C. Wolchok

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BioTester

2015

Development of non-cell adhesive vascular grafts using supramolecular building blocks

G. C. van Almen, H. Talacua, B.D. Ippel, B.B. Mollet, M. Ramaekers, M. Simonet, A.I.P.M. Smits, C.V.C. Bouten, J. Kluin, P.Y.W. Dankers

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BioTester

2015

High-irradiance CXL combined with myopic LASIK: flap and residual stroma biomechanical properties studied ex-vivo

A.J. Kanellopoulos, G. Asimellis, B.Salvador-Culla, J. Chodosh, J.B. Ciolino

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UniVert

2015

High-irradiance CXL combined with myopic LASIK: flap and residual stroma biomechanical properties studied ex-vivo

A. J. Kanelloploulos, G. Asimellis, B. Salvador-Culla, J. Chodosh, J.B. Ciolino

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BioTester

2015

Improved geometry of decellularized tissue engineered heart valves to prevent leaflet retraction

B. Sanders, S. Loerakker, E.S. Fioretta, D.J.P. Bax, A. Driessen-Mol, S.P.Hoerstrup, F.P.T Baaijens

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BioTester

2015

Leaflet stress and strain distributions following incomplete transcatheter aortic valve expansion

M. Abbasi, A.N. Azadani

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BioTester

2015

Methods for using 3-D ultrasound speckle tracking in biaxial mechanical testing of biological tissue samples

C.H. Yap, D.W. Park, D. Dutta, M. Simon, K. Kim

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BioTester

2015

Nanocomposite silicone hydrogels with a laser-assisted surface modification for inhibiting the growth of baterial biofilm

P. Yin, G.B. Huang, W.H. Tse, Y.G. Bao, J. Denstedt, J. Zhang

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BioTester

2015

Regional and depth variability of porcine meniscal mechanical properties through biaxial testing

A. Kahlon, M.B. Hurtig, K.D. Gordon

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BioTester

2015

Superior tissue evolution in slow degrading scaffolds for valvular tissue engineering

M. Brugmans, S. Soekhradj-Soechit, D. van Geemen, M.A.J. Cox, C. Bouten, F.P.T. Baaijens, A. Driessen-Mol

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BioTester

2015

The Biomechanics of Eyelid Tarsus Tissue

M.T. Sun, D. Pham, A.J. O'Conner, J. Wood, R. Casson, D. Selva, J.J. Costi

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BioTester

2014

Cardiac Function of the Naked Mole-Rat: Echophysiological Responses to Working Underground

K.M. Grimes, A. Voorhees, Y.A. Chiao, H-C. Han, M.L. Lindsey, R. Buffenstein

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BioTester

2014

Directional Biomechanical Properties of Porcine Skin Tissue

H-Y. Huang, S. Huang, C.P. Frazier, P.M. Prim, O. Harrysson

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UniVert

2014

Intrastromal Application of Riboflavin for Corneal Crosslinking

T.G. Seiler, I. Fischinger, T. Senfft, G. Schmidinger, T. Seiler

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MicroSquisher

2014

Mesenchymal morphogenesis of embryonic stem cells dynamically modulates the biophysical microtissue niche

M.A. Kinney, R.Saeed, T.C. McDevitt

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BioTester

2014

Modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues

G. Argento, N. de Jonge, S.H.M. Sontjens, C.W.J. Oomens, C.V.C. Bouten, F.P.T. Baaijens

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BioTester

2014

Should a native depth-dependent distribution of human meniscus constitutive components be considered in FEA-models of the knee joint?

J.M. Parraga Quiroga, P. Emmans, W. Wilson, K. Ito, C.C. van Donkelaar

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BioTester

2014

Strain-dependent modulation of macrophage polarization within scaffolds

V. Ballotta, A. Dressen-Mol, C.V.C. Bouten, F.P.T. Baaijens

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BioTester

2014

Structural and mechanical adaptations of right ventrical free wall myocardium to pressure overload

M.R. Hill, M.A. Simon, D. Valdez-Jasso, H.C. Champion, M.S. Sacks

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BioTester

2014

The biaxial biomechanical behavior of adominal aortic aneurysm tissue

S.A. O'Leary, D.A. Healey, E.G. Kavanagh, M.T. Walsh, T.M. McGloughling, B.J. Doyle

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BioTester

2014

The biaxial mechanical behaviour of abdominal aortic aneurysm intraluminal thrombus: Classification of morphology and the determination of layer and region specific properties

S.A. O'Leary, E.G. Kavanagh, P.A. Grace, T.M. McGloughlin, B.J. Doyle

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BioTester

2014

The impact of long term freezing on the mechanical properties of porcine aortic tissue

S. O'Leary, B. Doyle, T. McGloughlin

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BioTester

2014

Vascular Elastography: A Validation Study

R.G.P. Lopata, M.F.J. Peters, J. Nijs, C.W. Oomens, M.C.M. Rutten, F.N. van de Vosse

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BioTester

2013

A Nanocomposite Contact Lens for the Delivery of Hydrophilic Protein Drugs

J. Zhang, R. Bi, W. Hodge, P. Yin, W.H. Tse

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MicroSquisher

2013

Alginate Encapsulation Parameters Influence the Differentiation of Microencapsulated Embryonic Stem Cell Aggregates

Wilson, J.L., Ali Naijia, M., Saeed, R., McDevitt, T.C.

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BioTester

2013

Comparison of methods used to measure the thickness of soft tissues and their influence on the evaluation of tensile stress

S.A. O'Leary, B.J. Doyle, T.M. McGloughlin

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BioTester

2013

Corneal resistance to shear force after UVA-riboflavin cross-linking

A.P. Sondergaard, A. Ivarsen, J. Hjortdal

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BioTester

2013

In vitro fabrication of autologous living tissue-engineered vascular grafts based on prenatally harvested ovine amniotic fluid-derived stem cells

B. Weber, D. Kehl, U. Bleul, S. Sammut, L. Frese, A. Ksiazek, L Behr, J. Achermann, G. Stranzinger, J. Robert, B. Sanders, M. Sidler, C.E. Brokopp, S.T. Proulx, T. Frauenfelder, R. Schoenauer, M.Y.Emmert, V. Falk, S.P.Herstrup

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BioTester

2013

Mechanical Analysis of Ovine and Pediatric Pulmonary Artery for Heart Valve Stent Design

M.S. Cabrera, C.W.J. Oomens, C.V.C. Bouten, A.J.J.C. Bogers, S.P. Hoerstrup, F.P.T. Baaijens

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BioTester

2013

Mechanics of the pulmonary valve in the aortic position

A.L.F. Soares, D. van Geeman, A.J. van den Bogaerdt, C.W.J. Oomens, C.V.C. Bouten, F.P.T. Baaijens

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BioTester

2013

Reduction of Stromal Swelling Pressure after UVA-Riboflavin Cross-Linking

A.P. Sondergaard, A. Ivarsen, J. Hjortdal

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BioTester

2012

A Murine Experimental Model for the Mechanical Behavior of Viable Right-Ventricular Myocardium

D. Valdez-Jasso, M.A. Simon, H.C. Champion, M.S. Sacks

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BioTester

2012

An Examination of the Mechanical Properties of the Annulus Fibrosus: The Effect of Vibration on the Intra-lamellar Matrix Strength

Diane Gregory, J. Callaghan

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BioTester

2012

Application of Simple Biomechanical and Biochemical Tests to Heart Valve Leaflets: Implications for Heart Valve Characterization and Tissue Engineering

H-Y. Huang, B.N. Balhouse, S. Huang

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BioTester

2012

Biomechanical Properties of the Transverse Carpal Ligament Under Biaxial Strain

Michael Holmes, S. Howarth, J. Callaghan, P. Keir

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BioTester

2012

Multi-Scale Mechanical Characterization of Scaffolds for Heart Valve Tissue Engineering

G. Argento, M. Simonet, C.W.J. Oomens, F.P.T. Baaijens

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MicroSquisher

2012

Stiffening of Human Mesenchymal Stem Cell Spheroid Mircoenvironments Induced By Incorporation of Gelatin Microparticles

P. R. Baraniak, M.T. Cooke, R. Saeed, M.A. Kinney, K.M. Fridley, T.C. mcDevitt

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BioTester

2011

A Comparison of Uniaxial and Biaxial Mechanical Properties of the Annulus Fibrosus: A Porcine Model

Diane Gregory, J. Callaghan

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BioTester

2011

Does Vibration Influence the Initiation of Intervertebral Disc Herniation

Diane Gregory, J. Callaghan

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BioTester

2011

Novel Lap Test Determines the Mechanics of Delamination Between Annular Lamellae of the Intervertebral Disc

D. Gregory, J. Veldhuis, C. Horst, W. Brodland, J. Callaghan

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BioTester

2011

Surfactant Assisted Incorporation of Single-Walled Carbon Nanotubes Into a Chitosan-polyvinylpyrrolidone Polymer

T. Davis, J. Zhang, J.E. Herrera

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BioTester

2010

An Examination of the Influence of Strain Rate on Subfailure Mechanical Properties of the Annulus Fibrosus

D. Gregory, J. Callaghan

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BioTester

2010

Biaxial Mechanical Testing of Human Sclera

A. Eilaghi, J. Flanagan, I. Tertinegg, C. Simmons, W. Brodland, R. Ethier

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BioTester

2010

Effects of Sclera Stiffness on Biomechanics of the Optic Nerve Head in Glaucoma

A. Eilaghi

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BioTester

2010

Effects of Sclera Stiffness Properties on Optic Nerve Head Biomechanics

A. Eilaghi, J. Flanagan, C. Simmons, R. Ethier

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MicroSquisher

2009

Cellular Interfacial and Surface Tensions Determined From Aggregate Compression Tests Using a Finite Element Model. HFSP Journal

Brodland, G.W., Yang, J., Sweny, J.

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BioTester

2009

Fabrication of Nanofiber Reinforced Protein Structures for Tissue Engineering

V. Beachley, X. Wen

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BioTester

2009

Strain Uniformity in Biaxial Specimens is Highly Sensitive to Attachment Details

A. Eilaghi, J. Flanagan, G.W. Brodland, R. Ethier

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BioTester

2009

The Influence of the Tensile Material Properties of Single Annulus Fibrosus Lamellae and the Interlamellar Matrix Strength on Disc Herniation and Progression

D. Gregory

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