產品名稱 Abacavir - LKT Labs
產品貨號 A0401
產品價格 現(xiàn)貨詢價，電話：010-67529703
產品規(guī)格 10 mg 25 mg 50 mg
產品品牌 lktlabs
產品概述
產品詳情 Abacavir

Description

Abacavir is a guanosine nucleoside analog reverse transcriptase inhibitor (NRTI) that is clinically used to treat HIV infection. Abacavir exhibits antiviral activity. This compound also inhibits guanylyl cyclase and telomerase activity.

Product Info

Cas No.

136470-78-5

Purity

≥98%

Formula

C14H18N6O

Formula Wt.

286.33

IUPAC Name

[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol

Solubility

H2O: ≥17?mg/mL DMSO 78 mg/mL Ethanol <1mg/mL

Appearance

White to off white powder

Shipping and Storage

Store Temp

Ambient

Ship Temp

Ambient

Downloads

MSDS

A0401 MSDS PDF

Info Sheet

A0401 Info Sheet PDF

Brochures

Antivirals Booklet

References

Leeansyah E, Cameron PU, Solomon A, et al. Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging. J Infect Dis. 2013 Apr;207(7):1157-65. PMID: 23303810.

Baum PD, Sullam PM, Stoddart CA, et al. Abacavir increases platelet reactivity via competitive inhibition of soluble guanylyl cyclase. AIDS. 2011 Nov 28;25(18):2243-8. PMID: 21941165.

Ribera E, Tuset M, Martín M, et al. Characteristics of antiretroviral drugs. Enferm Infecc Microbiol Clin. 2011 May;29(5):362-91. PMID: 21531048.
產品資料