| 產(chǎn)品詳情 |
 Descriptionβ-Carotene is a red-orange terpene pigment originally found in various plants and fruits; it is a prodrug for vitamin A. β-Carotene exhibits antioxidative, cytoprotective, anticancer, anti-inflammatory, anti-hyperlipidemic, and anti-obesity activities. β-Carotene is used in research models to quantify antioxidative activity. In bone marrow cells, β-carotene protects against radioactive isotope-induced DNA damage. In breast cancer cells, this compound induces cell cycle arrest and apoptosis, decreasing cellular viability. β-Carotene decreases total cholesterol, VLDL and LDL levels, suppresses expression of SREBP2 and LDL-R, and increases expression of PPARα in vivo. In other animal models, this compound decreases body fat and adipocyte size and suppresses TNF-α-induced inflammation. Product Info| Cas No. | 7235-40-7 |
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| Purity | ≥97% |
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| Formula | C40H56 |
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| Formula Wt. | 536.87 |
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| Chemical Name | β,β-Carotene |
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| IUPAC Name | 1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,
16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-1,3,5,7,9,11,
13,15,17-nonaenyl]cyclohexene |
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| Synonym | Carotaben, Provatene, Solatene |
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| Melting Point | 183°C |
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| Solubility | Insoluble in water. Sparingly soluble in ethanol. Soluble in benzene or chloroform. |
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| Appearance | Dark Yellowish Red Powder |
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Shipping and Storage| Store Temp | -20°C |
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| Ship Temp | Ambient |
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ReferencesAbdel-Mageed WM, Bayoumi SA, Salama AA, et al. Antioxidant lipoxygenase inhibitors from the leaf extracts of Simmondsia chinensis. Asian Pac J Trop Med. 2014 Sep;7S1:S521-6. PMID: 25312177. Berti AP, Düsman E, Mariucci RG, et al. Antimutagenic and radioprotective activities of beta-carotene against the biological effects of iodine-131 radiopharmaceutical in Wistar rats. Genet Mol Res. 2014 Mar 31;13(1):2248-58. PMID: 24737473. Gloria NF, Soares N, Brand C, et al. Lycopene and beta-carotene induce cell-cycle arrest and apoptosis in human breast cancer cell lines. Anticancer Res. 2014 Mar;34(3):1377-86. PMID: 24596385. Silva LS, de Miranda AM, de Brito Magalh?es CL, et al. Diet supplementation with beta-carotene improves the serum lipid profile in rats fed a cholesterol-enriched diet. J Physiol Biochem. 2013 Dec;69(4):811-20. PMID: 23645541. Di Tomo P, Canali R, Ciavardelli D, et al. β-Carotene and lycopene affect endothelial response to TNF-α reducing nitro-oxidative stress and interaction with monocytes. Mol Nutr Food Res. 2012 Feb;56(2):217-27. PMID: 22162208. Amengual J, Gouranton E, van Helden YG, et al. Beta-carotene reduces body adiposity of mice via BCMO1. PLoS One. 2011;6(6):e20644. PMID: 21673813. |
