Description
γ-3 Melanocyte-stimulating hormone (γ-3 MSH) is an endogenous POMC-derived peptide found in the pituitary that activates melanocortin receptors. γ-3 MSH promotes release of melanin by melanocytes and modulates adrenocorticotropic hormone (ACTH)-induced steroidogenesis.
References
Slominski A, Costantino R, Wortsman J, et al. Melanotropic activity of gamma MSH peptides in melanoma cells. Life Sci. 1992;50(15):1103-8. PMID: 1556905.
Sharp B, Sowers JR. Adrenocortical response to corticotropin is inhibited by gamma 3-MSH antisera in normotensive and spontaneously hypertensive rats. Biochem Biophys Res Commun. 1983 Jan 27;110(2):357-63. PMID: 6301449.
