Description
β-Casomorphin is a peptide fragment of casein that exhibits antioxidative and anti-fibrotic activities. In vivo, β-casomorphin improves high glucose-induced changes in oxidative enzyme secretion and activity. β-Casomorphin also decreases urinary glucose and protein levels as well as serum creatine and TGF-β1 in animal models of diabetes, preventing renal interstitial fibrosis.
References
Zhang W, Miao J, Wang S, et al. The protective effects of beta-casomorphin-7 against glucose -induced renal oxidative stress in vivo and vitro. PLoS One. 2013 May 3;8(5):e63472. PMID: 23658831.
Zhang W, Miao J, Ma C, et al. β-Casomorphin-7 attenuates the development of nephropathy in type I diabetes via inhibition of epithelial-mesenchymal transition of renal tubular epithelial cells. Peptides. 2012 Aug;36(2):186-91. PMID: 22687367.
