產(chǎn)品名稱Chrysin
產(chǎn)品貨號(hào)C80105
產(chǎn)品價(jià)格現(xiàn)貨詢價(jià),電話:010-67529703
產(chǎn)品規(guī)格C80105
產(chǎn)品品牌sigmaaldrich
產(chǎn)品詳情

Description

Packaging

25 g in glass bottle

Application

??Chrysin has been used to study the effect of bioflavonoids on the inhibition of ATP synthase in Escherichia coli.
??It has been used to study the effect of Chrysin on eIF4E (eukaryotic translation initiation factor 4E) expression in AGS cell (human gastric carcinoma cell) line.
??It has been used to study the effect of chrysin on human ovarian cancer cells.

Biochem/physiol Actions

Chrysin is a flavonoid and an analog of apigenin. It inhibits aromatase and also suppresses human immunodeficiency virus (HIV) activation in models with latent infection. Chrysin exhibits anti-inflammatory and anti-oxidant effects. This molecule induces apoptosis in various cells, thereby exhibiting cancer chemopreventive activity. Chrysin can modulate the activity of GABAA (Type-A γ-aminobutyric acid) and GABAC receptors, it downregulates expression of PCNA (proliferating cell nuclear antigen), reduces activity of CDK2 (cyclin-dependent kinase 2) and CDK4 and induces p38-MAPK (mitogen-activated protein kinase) activation.

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