SH2D1A Antibody is a Rabbit Polyclonal antibody against SH2D1A. SH2D1A and SH2D1B are small, adaptor proteins with a single SH2-domain that play important signal transduction roles mediated by the signaling lymphocytic activation molecule (SLAM) family receptorsSH2D1A (also called SAP or SLAM-associated protein) is frequently mutated in patients with X-linked lymphoprolifeRative disease (Duncan’s disease), which is characterized by extreme susceptibility to Epstein-Barr virus; approximately 50 different SH2D1A mutations have been reported to dateThe single SH2D1B gene in humans (also called EAT-2 or Ewings sarcomas/FLI1-activated transcript 2) is present as a pair of duplicated EAT-2A and EAT-2B genes with identical genomic organization in mouse and Rat.

Target	SH2D1A
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Tested Applications	ELISA, WB, IHC
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant protein of human SH2D1A.
Purification	Affinity Chromatography.
Form	Liquid
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Swiss Prot	O60880
GeneID	4068
Gene Symbol	SH2D1A
Buffer	PBS, pH7.3, containing 0.02% sodium azide and 50% Glycerol.
UNSPSC Code	12352203
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.