SGK1 Antibody is a Rabbit Polyclonal antibody against SGK1. Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to AktSGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocorticoidsSGK activation can be accomplished via HGF PI3K-dependent pathways and by integrin-mediated PI3K-independent pathwaysInduction and activation of SGK has been implicated in activating the modulation of anti-apoptotic and cell cycle regulationSGK also plays an important role in activating certain potassium, sodium, and chloride channels, suggesting its involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretionSGK is negatively regulated by ubiquitination and proteasome degradationThe MAP kinase family member BMK1 interacts with and activates SGK by phosphorylation at serine 78.

Target	SGK1
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Tested Applications	ELISA, WB, IHC
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant protein of human SGK1.
Purification	Affinity Chromatography.
Form	Liquid
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Swiss Prot	O00141
GeneID	6446
Gene Symbol	SGK1
Buffer	PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
UNSPSC Code	12352203
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.