SQSTM1 Antibody is a Rabbit Polyclonal antibody against SQSTM1. This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Target	SQSTM1
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB, IHC, IF/ICC, IP, FCM
Recommended dilutions	WB: 1/1000 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200, IP: 1/20 - 1/50, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant protein of human SQSTM1.
Purification	Affinity purified.
Form	Liquid
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Calculated MW: 38 kDa/47 kDa Observed MW: 57 kDa
Swiss Prot	Q13501
GeneID	8878
Gene Symbol	SQSTM1
Concentration	> 1 mg/ml
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
UNSPSC Code	12352203
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.