RYR1 Antibody is a Rabbit Polyclonal antibody against RYR1. Recombinant Human RYR1 ProteinCalcium Channel That Mediates The Release Of Ca2+ From The Sarcoplasmic Reticulum Into The Cytoplasm And Thereby Plays A Key Role In Triggering Muscle Contraction Following Depolarization Of T-TubulesRepeated Very High-Level Exercise Increases The Open Probability Of The Channel And Leads To Ca2+ Leaking Into The CytoplasmCan Also Mediate The Release Of Ca2+ From Intracellular Stores In Neurons, And May Thereby Promote Prolonged Ca2+ Signaling In The BrainRequired For Normal Embryonic Development Of Muscle Fibers And Skeletal MuscleRequired For Normal Heart Morphogenesis, Skin Development And Ossification During Embryogenesis.
| Target |
RYR1 |
| Reactivity |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
ELISA, IF/ICC |
| Recommended dilutions |
IF: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant human Ryanodine receptor 1 protein (1-534AA). |
| Purity |
> 95% |
| Purification |
Protein G. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Swiss Prot |
P21817
|
| GeneID |
6261
|
| Gene Symbol |
RYR1 |
| OMIM |
1891
|
| NCBI Accession |
NP_000531.2
NM_000540.2
|
| Buffer |
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |