PDCD10 Antibody is a Rabbit Polyclonal antibody against PDCD10. This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
| Target |
PDCD10 |
| Reactivity |
Human, Rat |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
IHC |
| Recommended dilutions |
IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Recombinant fusion protein of human PDCD10. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 24 kDa |
| Swiss Prot |
Q9BUL8
|
| GeneID |
11235
|
| Gene Symbol |
PDCD10 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| UNSPSC Code |
12352203 |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |