Phospho-Aurora Kinase (Thr288) Antibody detects endogenous levels of Aurora Kinase only when phosphorylated at Threonine 288. The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression.

Target	Aurora Kinase (pT288)
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Purification	Purified by affinity chromatography.
Conjugation	Unconjugated
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Swiss Prot	O14965
GeneID	6790
Gene Symbol	AURKA
OMIM	603072
Enzyme Commission Number	EC 2.7.11.1
HGNC	11393
Ensembl	ENSG00000087586
Buffer	PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
UNSPSC Code	12352203
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.