LIG3 Antibody is a Rabbit Polyclonal antibody against LIG3. This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

Target	LIG3
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB, IF/ICC, IP
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100, IP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	Recombinant protein of human LIG3.
Purification	Affinity purified.
Form	Liquid
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Calculated MW: 95 kDa/102 kDa/106 kDa/112 kDa Observed MW: 113 kDa
Swiss Prot	P49916
GeneID	3980
Gene Symbol	LIG3
Concentration	> 1 mg/ml
Buffer	PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code	12352203
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.