NBN Antibody is a Rabbit Polyclonal antibody against NBN. Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Target	NBN
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB, IF/ICC, FCM
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/20 - 1/50, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	A synthetic peptide of human NBN.
Purification	Affinity purified.
Form	Liquid
Isotype	IgG
Conjugation	Unconjugated
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight	Calculated MW: 84 kDa Observed MW: 105 kDa
Swiss Prot	O60934
GeneID	4683
Gene Symbol	NBN
Concentration	> 1 mg/ml
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
UNSPSC Code	12352203
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.