Phospho-VEGFR2 (Tyr1059) Antibody detects endogenous levels of VEGFR2 only when phosphorylated at Tyrosine 1059. VEGFR-2 is a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2.

Target	VEGFR2 (pY1059)
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Tested Applications	WB
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Purification	Purified by affinity chromatography.
Conjugation	Unconjugated
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Swiss Prot	P35968
GeneID	3791
Gene Symbol	KDR
OMIM	191306
Enzyme Commission Number	EC 2.7.10, EC 2.7.10.1
HGNC	6307
Ensembl	ENSG00000128052
Buffer	PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
UNSPSC Code	12352203
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.