Recombinant Human Polymerase I and transcript release factor,isoform 3 (PTRF)
Description
1-390aa, full length protein. MW: 22,597 Da. Purity >85% (SDS-PAGE). This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3 end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the form
[caveolae-associated protein 1; Caveolae-associated protein 1; caveolae-associated protein 1; polymerase I and transcript release factor; caveolae associated protein 1; Cavin-1; Polymerase I and transcript release factor]