Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3) (Middle Region)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human, mouse, rat
Isotype
n/a
Format
affinity purified
Size
50 μg
Concentration
n/a
Applications
Western Blotting (WB)
Reviews / Ratings
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Description
NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.
Immunogen
NR1 I3 antibody was raised using the middle region of NR1 3 corresponding to a region with amino acids PVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDG