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Description
This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. This NR2C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-545 amino acids from the C-terminal region of human NR2C1.
Immunogen
Human NR2C1.
Other Names
NR2C1; Orphan nuclear receptor TR2; Testicular orphan receptor-2; TR2; TR2 nuclear hormone receptor; TR2-11; Testicular receptor 2; Nuclear receptor subfamily 2 group C member 1