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Description
Mouse IgG monoclonal Picoband? antibody for beta Catenin detection. Tested with WB, IHC-P, ICC, FCM in Human;Mouse;Rat. No cross reactivity with other proteins. Catenins are proteins found in complexes with cadherin cell adhesion molecules of animal cells. The first two catenins that were identified became known as alpha-catenin and beta-catenin. Alpha-catenin can bind to beta-catenin and can also bind actin. Beta-catenin binds the cytoplasmic domain of some cadherins. Beta-catenin is an adherens junction protein. It plays an important role in various aspects of liver biology including liver development (both embryonic and postnatal), liver regeneration following partial hepatectomy. HGF-induced hepatpomegaly, liver zonation, and pathogenesis of liver cancer.
Immunogen
E. coli-derived human beta Catenin recombinant protein (Position: A2-K233).