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Description
SENP1 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SENP deconjugates SUMO1 from HIPK2 and from HDAC1, which decreases the transcriptional repression activity of the latter. This SENP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-590 amino acids from the C-terminal region of human SENP1.
Immunogen
Human SENP1.
Other Names
SENP1; Sentrin-specific protease 1; Sentrin/SUMO-specific protease SENP1; SUMO1/sentrin specific peptidase 1; SUMO1/sentrin specific protease 1; SuPr-2; SUMO1; sentrin specific protease 1