Glia maturation factor beta(GMF beta) coded by GMFb gene at chromosome 14 in mouse, is identical to human GMF beta, with the exception of two amino acid residues. It is a brain-specific protein that belongs to the actin-binding proteins (ADF) structural family, and plays an important role in the upstream regulation of excessive production and the releasing of proinflammatory cytokines/chemokines in brain cells, leading to the destruction of oligodendrocytes, the myelin forming cells, and neurons. Less than 1EU/μg of rMuGMF beta as determined by LAL method. MW: 16.4 kDa. Purity >97% pure by SDS-PAGE and HPLC analyses.