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Description
Pre-mRNA-binding protein required for splicing of both U2-and U12-type introns. Selectively interacts with the 3'-splice site of U2-and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing. This ZRSR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 453-482 amino acids from the C-terminal region of human ZRSR2.
Immunogen
n/a
Other Names
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2; U2AF1-RS2; U2AF1L2; U2AF1RS2; URP; CCCH type zinc finger; RNA-binding motif and serine/arginine rich protein 2; Renal carcinoma antigen NY-REN-20; U2 (RNU2) small nuclear RNA auxiliary factor 1-like 2; U2AF35-related protein; ZRSR2; ZC3H22; Zinc Finger CCCH-Type, RNA Binding Motif And Serine/Arginine Rich 2