SPARC Like Protein 1 (SPARCL1), BioAssay? ELISA Kit (Human)
Description
SPARCL1 (SPARC-Like Protein 1), also known as HEVIN, is a protein that in humans is encoded by the SPARCL1 gene. The cells in high endothelial venules (HEVs) in lymphoid tissues have a plump, almost cuboidal, appearance and support high levels of lymphocyte extravasation from blood, possibly due to the presence of desmosome-like junctions rather than tight junctions in the HEVs. In chronic inflammation, the activated endothelium of nonlymphoid tissues acquires an HEV-like morphology and function. SPARCL1 is highly expressed in HEV and is thought to contribute to the induction or maintenance of features of the HEV endothelium that facilitate lymphocyte migration. Sample Type: Cell culture supernates and serum. Intended Use: For quantitative detection of human SPARCL1 in cell culture supernates and serum. Sensitivity: <10pg/ml Range: 46.9-3000pg/ml Specificity: Natural and recombinant human SPARCL1 Test Principle: This human SPARCL1 BioAssay? ELISA Kit was based on standard sandwich enzy