Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000
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Description
Cdc45L Polyclonal Antibody. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported.
Immunogen
n/a
Other Names
CDC 45;CDC 45L;CDC45 (cell division cycle 45, S.cerevisiae homolog) like;CDC45;CDC45 cell division cycle 45 like;CDC45 like;CDC45 related protein;CDC45_HUMAN;CDC45L2;Cell division control protein 45 homolog;Cell division cycle 45 like 2;Cell division cycle 45 like;PORC PI 1;PORC-PI-1;