Tumor necrosis factor receptor superfamily member 1B, 23-257aa, Human, His tag, Baculovirus
Description
Purity: > 95% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.. TNFRSF1B, also known as tumor necrosis factor receptor superfamily member 1B, mediates most of the metabolic effects of TNF-alpha. The receptor isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. Further, high plasma levels of TNFRSF1B were significantly associated with increased incidence of coronary heart disease. Recombinant human TNFRSF1B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.