Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 40% glycerol,2mM DTT, 0.1mM PMSF, 1mM EDTA. Muted homolog, also known as MuTED, is involved in the development of lysosome related organelles, such as melanosomes and platelet dense granules. MuTED interacts with pallidin, dystrobrevin binding protein 1 and CNO/cappuccino. It is part of the biogenesis of lysosome related organelles complex 1 (BLOC1). Also, MuTED is ubiquitously expressed with higher levels in brain, bone marrow, kidney, and liver and lower levels in skeletal muscle. Recombinant human MuTED protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.