Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.. PDCD1, also known as programmed cell death protein 1, is a type 1 transmembrane glycoprotein, and is an immune-receptor belonging to the CD28/CTLA4 family. This protein is expressed on the surface of activated T-cell, B-cell, macrophages, myeloid cells and subset of thymocytes. Also, it inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4 and IL-10. As a cell surface molecule, it regulates the adaptive immune response. Recombinant human PDCD1, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Size
250ug, 50ug, 10ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Programmed cell death protein 1, PDCD1, CD279, hPD-1, hPD-l, hSLE1, PD-1, PD1, SLEB2