p53 is a tumor suppressor that is regulated by transcriptional, post-transcriptional, and post-translational mechanisms in response to stress. Studies demonstrate that p53 is critical for the prevention of tumorigenesis and may potentially be involved in at least half of all known cancers. p53 functions as a transcription factor to regulate genes involved in apoptosis, cell cycle, senescence, metabolism, angiogenesis, immunity, differentiation, and migration. Moreover, p53 is phosphorylated at multiple sites, including Ser15, following DNA damage. Sample Types: Human cell culture, serum. Sample Size: 50 μL. Range: 0.78 - 50 U/mL. Sensitivity: 0.33 U/mL. Time: 3hr 10min
Size
96 wells
Concentration
n/a
Applications
Immunoassays. Research Use Only. Not for Use in Diagnostic Procedures.