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Description
Function: Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes, in particular endocytosis.Catalytic activity: GTP + H(2)O = GDP + phosphate.Subcellular location: Cytoplasm. Cytoplasm ?? cytoskeleton. Also known as: Dynamin-1, D100, DNM, EC 3.6.5.5, B dynamin, DNM 1, DNM1, Dynamin, Dynamin BREDNM19, Dynamin1.
Immunogen
A synthetic peptide from the c-terminal region of rat Dynamin 1 conjugated to an immunogenic carrier protein was used as the antigen. The antigen is homologous in human and mouse.