Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.. TNFRSF10B, also known as tumor necrosis factor receptor superfamily member 10B isoform 1, is a member of receptors for the cytotoxic ligand TNFSF10/TRAIL. It can be activated by tumor necrosis factor-related apoptosis inducing ligand, and transduces an apoptosis signal. This protein promotes the activation of NF-kappa-B. Defects in this protein causes of head and neck squamous cell carcinomas. Recombinant human TNFRSF10B protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.