Purity: > 90% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl . CLIC1 (Chloride intracellular channel 1), also referred to as NCC27, is a member of the highly conserved family of chloride ion channels that function in both soluble and integral membrane forms. This protein is a monomeric protein that contains a redox-active site similar to glutaredoxin; it functions as an anion-selective channel. It forms a dimer when oxidized and is then able to form chloride ion channels in bilayers and vesicles, whereas a reducing environment prevents this from occurring. Recombinant human CLIC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Size
0.5mg, 100ug, 20ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Chloride intracellular channel protein 1, G6, NCC27, Chloride intracellular channel protein 1 hRNCC, Nuclear chloride ion channel 27, p64CLCP, Chloride channel ABP, Chloride intracellular channel 1, CLIC 1, NCC 27, Nuclear chloride ion channel protein, Regulatory nuclear chloride ion channel protein, RNCC protein.