Purity: > 85 % by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) 1M urea, 5% Glycerol.. PINK1 is a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this protein cause one form of autosomal recessive early-onset Parkinson disease. Recombinant human PINK protein was expressed in E.coli and purified by using conventional chromatography techniques.