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Description
Rabbit Anti-AIRE (Phosphorylated S156) Polyclonal Antibody (PTM-CBPAB-0096YC). Provided herein is a Rabbit polyclonal antibody against Autoimmune Regulator. The antibody can be used for immunoassay techniques, such as WB, ELISA. AIRE is a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).