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Description
Anti-RNA Polymerase II RPB5. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The common components of RNA polymerases I, II, and III synthesize ribosomal RNA precursors, mRNA precursors, and many functional non-coding RNAs and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, RPB5 is part of the lower jaw that surrounds the central large cleft and is believed to grab the incoming DNA template. It seems to be the major component in this process.
Immunogen
Recombinant protein
Other Names
DNA-directed RNA polymerases I, II, and III subunit RPABC1, PolR2E, RNA polymerases I, II, and III subunit ABC1, RPA7, RPC9, W0014