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Description
APC anti-Annexin A1. Annexin1 (also known as Lipocortin-1) is a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. Phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins, and leukotrienes. Lipocortin-1 has phospholipase A2 inhibitory activity, thus therefore it is an anti-inflammatory protein.
Immunogen
This monoclonal antibody was raised against AG1523 human fibroblast cells.
Other Names
Lipocortin-1, p35, annexin-1, calpactin-2, calpactin II, lipocortin I, chromobindin-9, annexin I (lipocortin I), phospholipase A2 inhibitory protein