Recombinant Mouse Wilms tumor protein homolog (Wt1)
Description
1-449aa, Full length protein. MW: 54,943 Da. Purity >85% (SDS-PAGE). This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a prolineglutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm s tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. Th