A gut peptide; reduces [125I]-glucagon binding to rat liver plasma membranes and a glucagon antibody in a concentration-dependent manner; induces insulin secretion in a glucose-and concentration-dependent manner in perfused rat pancreas; increases glucose absorption in isolated rat small intestine and enterocytes; inhibits pentagastrin-stimulated gastric acid secretion in a dose-dependent manner in rats from 25-450 pmol/kg; increases plasma concentrations of insulin and glucose in Holstein cattle,